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Lifestyle changes may support symptom improvement, but only a healthcare provider can guide treatment

Due to the secretion of signalling molecules and cytokines, the cross-talk between microglia and astrocytes is enhanced, which can lead to vascular-endothelial dysfunction and damage to bloodbrain barrier (BBB) permeability

Research proposes that while it may influence senescence-associated pathways, it appears to preserve FOXO4s antioxidative transcriptional activity

The activity of PNPO is essential for the synthesis of PLP, which is the only theoretically effective therapeutic agent, and must be taken every 6 hours

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