OTUD7B deubiquitinates SQSTM1/p62 and promotes IRF3 degradation to regulate antiviral immunity
Although p53-induced downregulation of SLC7A11 could partially inhibit cystine uptake, the overall effect on GSH/GSSG ratio and glutathione levels was less
doi: 10.3389/fimmu.2025.1711756 Received 23 September 2025 Accepted 31 October 2025 Published 19 November 2025 Volume 16 - 2025 Edited by Jean-louis Mege, Aix-Marseille Universit, France Reviewed by Nadja Freund, Ruhr University Bochum, Germany Namrata Anand, University of Chicago Medical Center, United States Updates Copyright 2025 Su, Li, Yang, Yang, Wang, Ren, Bao, Lao and Luan
It is a tripeptide composed of three amino acidscysteine, glycine, and glutamic acid
IGF-1 , 5-AGGAAGTACATTTGAAGAACGCAAGT-3 (forward), 5-CCTGCGGTGGCATGTCA-3 (reverse)