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Each subject received in a random order a single subcutaneous dose of 1.2 mg liraglutide and placebo at an interval of 48 h, with subsequent clinical follow-up in the metabolic ward, during which blood pressure was monitored for the following 24-h and 24 h urinary samples were collected to assess sodium excretion

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247,248 The key targets of the PI3K/AKT pathway and their related regulatory mechanisms are shown in Fig

Some of the most common side effects in people taking these medications are gastrointestinal, such as vomiting and nausea

All animal experiments were approved by the Animal Experimentation Ethics Committee of Zhejiang University (Approval No