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Increased oxidative stress can affect blood vessel dilation, neurotransmitter signaling, and mitochondrial functioneach of which may play a role in migraines (Yilmaz 2007

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2023:chap 26

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At 36 weeks, retatrutide led to a maximum HbA1c reduction of 2.2%, while dulaglutide reduced it by 1.4%, and the placebo group by 0.3%

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The severity of side effects varies as per the dosage of the treatment

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