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5.1 Limitations Most of the studies yet performed regarding SID and SIH employed observational designs, and data derived from randomised controlled clinical studies are lacking

While this is a key research area, we propose that further investigations should verify whether GLP-1RAs may also affect cognitive and behavioral symptoms seen in psychosis, as suggested by their potential to influence neurobiological (for example, immune function) and neuropsychological (for example, reward) mechanisms that are known to be disrupted in psychotic illness

Hall et al., 2012), and PDD (Hall et al., 2012)

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