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However, when the structural and functional integrity of neural cells is compromised and the permeability of the bloodbrain barrier increases, it disrupts blood biomarkers, allowing GFAP to be released from tissues into the bloodstream

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Alhadeff, PhD, senior study author After reviewing this study, Shruti Pandiri, MD, assistant professor of medicine in the Division of Endocrinology with the Center for Weight Loss & Metabolic Health at Hackensack University Medical Center in New Jersey, told MNT the findings of this study have the potential to lead to the development of GLP-1-based obesity drugs with improved tolerability