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the decisive Laws 2012 meta-analysis showing essentially no effect in healthy adults

Using invasive sampling methods, such as bronchoalveolar lavage (BAL) or transtracheal aspiration (TTA), the LRT has been shown to host a low-biomass core microbiota dominated by Pasteurellaceae, Mycoplasmataceae, Flavobacteriaceae, Clostridiaceae, and Prevotellaceae, while archaea, viruses, and eukaryotic microbes are rarely reported (Table 1) 8,110,111,112

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If you genuinely cannot eat enough to function or keep fluids down, contact your clinician

Further investigations are needed to comprehensively assess the functional and safety aspects of long-term Exe4 secretion