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7.5 Plant-based therapy and traditional knowledge Plant-based drugs have always been an essential component of anticancer drug discovery, as they serve as natural reservoirs of compounds with immense anticancer properties

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184 In gastric cancer, serum factors IL-6 and IL-8 can stimulate CD45 + CD33 low CD11b dim MDSCs to express ARG1 and ultimately inhibit CD8 + T cell function through the PI3K-AKT signaling pathway (Fig