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The light modifier subunit GCLM is enzymatically inactive but plays an important regulatory function by lowering the Km of GCLC for glutamate and raising the Ki for GSH [7, 8]

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titled Glutathione Stimulates Vitamin D Regulatory and Glucose-Metabolism Genes, Lowers Oxidative Stress and Inflammation, and Increases 25 OHD Levels in Blood: A Novel Approach to Treat 25-Hydroxyvitamin D Deficiency clearly outlines this relationship and describes how increasing GSH has been shown to increase the bioavailability of 25(OH)D

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