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In reaction to AD, astrocytes experience a shift in profile, one that is reactive and pro-inflammatory while losing homeostatic roles thus disrupting BBB integrity, ion and neurotransmitter buffering, and energy metabolism (Liddelow et al., 2017

In rats that were subjected to hypoxic conditions, there was a drastic decrease in V3 and ADP/t levels

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The sections were subsequently stained with hematoxylin for 1 min at room temperature