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In terms of weight loss at comparable time points, tirzepatide consistently outperforms semaglutide in clinical trials

Results Eligibility of the studies Figure 1 illustrates the flowchart summarizing the literature search and screening process for this NMA

Complete weight regain occurred in 23% of semaglutide, 21% of tirzepatide, and 27% of liraglutide users at 24 months

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A growing body of research highlights the potential cardiometabolic benefits of yerba mate, with reported outcomes including reductions in fasting blood glucose, decreases in body fat percentage, increases in serum antioxidant capacity, and reductions in biomarkers of lipid and protein oxidation 1