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The EMA is in the process of reviewing available data from clinical trials, post-marketing surveillance, and medical literature

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T gel =1.8 (% F127)+1.3 (% F68)+53 An equation is fitted to the data obtained and can be utilized to estimate the Mean Dissolution Time (hr) based on the gelation temperature of F127/F68 mixtures (for 17-25% F127 and 0-10% F68), using results obtained in examples above: MDT= 0.2 ( T gel )+8