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Gastric acid-reducing medicines such as omeprazole or ranitidine: Long-term use may contribute to vitamin B12 deficiency and may increase the need for supplementation

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Others who are more likely to be deficient are smokers, alcoholics and anyone with digestive disorders, such as Crohns disease or celiac

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For many patients, improvements can be felt within a few days, especially if your B12 levels were low to begin with