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Although it could be anticipated that the magnitude of glutathione increases would correlate with behavioral improvements as in other studies ( When examining the relationship between baseline glutathione levels, the responders ( n = 12) had significantly higher baseline concentrations of both total and reduced glutathione than baseline and non-responders ( n = 8)

The two human 3-hydroxysteroid dehydrogenases have been investigated in detail by Thomas and coworkers (e.g., + as a coenzyme remains as an intermediate bound to the enzyme prior to its isomerization to 4-AD