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Clin Cancer Res 20(21):5537-46, 2014

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The hippocampus, which is part of the temporal lobe of the cerebral cortices and important in memory formation, is highly sensitive to stress levels because of its many glucocorticoid receptors

To address health-related residual symptoms in the majority of SCD patients in the USA and around the world, it is crucial to maximize non-curative therapies, such as those that do not include stem cell or gene therapy but avoid or abort SCD effects