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Archived from the original on September 15, 2008

10.1158/2159-8290.CD-12-0095 18 ChenM.-H.TsaiS.-J.SuT.-P.LiC.-T.LinW.-C.ChengC.-M.et al (2022)

After 30 min of accommodation in normoxia (oxygen 20%), cultures were exposed to 24 or 48 h of hypoxia (oxygen 2%)

From regulating mood and energy to reducing inflammation and protecting against chronic diseases, studies show that this estrogen impacts nearly every aspect of well-being

These findings collectively identify the FOXO4-p53 axis as a potential pharmacological target in brain aging and highlight senolytic therapy as a promising strategy for altering diseases to postpone or reverse age-related cognitive decline