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Phase 2 liver disease data published in Nature Medicine (2024) identifies retatrutide as the compound with the most comprehensive hepatic fat reduction profile currently under clinical investigation, making it the correct peptide for NAFLD and MASH preclinical study designs

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Individuals with genetic variants associated with reduced GST activity or impaired antioxidant enzyme function may require higher glutathione support or more frequent dosing schedules

These include proteins, minerals, vitamins, essential fatty acids, dietary fibers, and other functional compounds as shown in Table 1 [34, 35]

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