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Melanin has the capacity to scavenge reactive oxygen species and to neutralize microorganisms and their harmful products

Unlike small-molecule drugs that may tolerate ambient conditions, these large protein molecules undergo conformational changes when exposed to heat, leading to degradation, aggregation, or denaturation

The spectrum of behavioral changes in Alzheimers disease

In patients with T2DM, cognitive deficits are classified into three broad stages according to severity: diabetes-related cognitive decline, mild cognitive impairment (MCI) and dementia ( Oxidative stress and mitochondrial dysfunction Oxidative stress is a serious imbalance between the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) and antioxidant defenses ( 2+ levels, which may have deleterious consequences