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There is a clear and known explanation mechanism for this

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In addition to GIPs role in promoting lipid storage in adipocytes 140 , the GIP receptor (GIPR) is found in neurons of the ARC, dorsomedial nucleus (DMH), and paraventricular nucleus of the hypothalamus 141

Lyophilized powder remains stable at room temperature (2025C) for months, but reconstituted peptide degrades rapidly above 8C