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However, there is only one approved drug, setmelanotide for POMC-LEPR deficiency [10], and there is no treatment for other POMC-MC4R pathway-deficient diseases, such as POMC-null, MSH-deficiency, and patients with PWS with obesity

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The 1990s saw continued research into GHRPs as potential clinical solutions for a variety of diseases and disorders, with the first studies to investigate GHRPs in growth hormone deficiencies

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The 25.4-fold increase in collagen IV when combined with hyaluronic acid indicates significant structural improvement potential

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Knapen LM, de Jong RG, Driessen JH, Keulemans YC, van Erp NP, De Bruin ML, Leufkens HG, Croes S, de Vries F

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