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2.13-3.74) or a dissecting aneurysm (OR = 2.24

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Within the geroscience framework 16 , the accelerated-aging phenotype in PWH provides an ideal clinical model to evaluate candidate geroprotective therapies, with findings potentially relevant to the general aging population

In particular, hypoxia was unique to CD8 + T cells and the G2-M checkpoint was shared by CD4 + T and plasma cells in the Hallmark gene set ( Figure 8I )

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