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Agarwal A, Dadge SD, Garg R, Chauhan D, Katekar R, Maity D, et al

Given that all these patients had established ASCVD, I would deem them under-treated with standard lipid-lowering therapy because the average LDL-C was 78 (goal LDL-C in this population is at least 70 and had never had apo B

This has significant mechanistic and therapeutic implications

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Historical Background and Scientific Context Scientific interest in DSIP emerged during the twentieth century as researchers sought to better understand naturally occurring peptide messengers and their role in biological signalling systems