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This work benefited from the equipment and framework of the COMP-HUB and COMP-R initiatives, funded by the Departments of Excellence program of the Italian Ministry for University and Research (MIUR, 2018-2022 and MUR, 2023-2027), and from the High Performance Computing facility of the University of Parma, Italy

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In addition, the functional expression of the mechanosensitive PIEZO1 channels in endometrial organoids, evaluated by monitoring intracellular calcium changes, more closely aligned with its activity in primary endometrial epithelial cells compared to the Ishikawa cell line, thereby further underscoring the superior functional mimicry of endometrial organoids