what is retatrutide for How Does Work? Doctor Explains Why It's So Effective Retatrutide: Evidence, Safety & Options

Rossetti L, Hu M

Better Overall Wellness: Regular use can lead to improved immune function and cardiovascular health

Retatrutide TRIUMPH-1 (2023) and TRIUMPH-2 (2024) TRIUMPH-1 (Jastreboff et al., NEJM 2023): 338 non-diabetic adults with obesity, 48 weeks at escalating doses: 12 mg dose: 24.2% weight loss 8 mg dose: 22.8% 4 mg dose: 17.5% Placebo: 2.1% TRIUMPH-2 (Rosenstock et al., Lancet 2024) confirmed effects in T2D patients with concurrent NAFLD improvement (hepatic fat reduction 54% at 24 weeks, 12 mg dose)

Hypokalemia (low potassium) This happens when rapidly increased red blood cells pull potassium from the blood

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