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Whereas, over-the-counter pills and stimulants present too many toxicities and are highly discouraged among the medical community

The SURMOUNT-4 trial (Aronne 2023, JAMA) showed that adults who stopped tirzepatide after 36 weeks regained an average of 14.0% of body weight over the next 52 weeks, while those who continued tirzepatide lost an additional 5.5% a 19.4% between-group difference

Readers can use the added context to bring sharper questions to a licensed provider before making a treatment, cost, or care decision

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But if you take too much, you could have more side effects, like an upset stomach