6 The development of chronic migraine is understood to be a gradual process, with predisposing risk factors interacting with genetic susceptibility and frequent headache pain to lower the threshold of migraine attacks and consequently increase the risk of chronic migraine
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Overproduction of ROS is detrimental for the embryo, resulting from impaired intracellular milieu and disturbed metabolism [17, 165]
Over time, plaques can narrow arteries or rupture, causing thrombosis and acute myocardial infarction ( Natural products used in TCM have shown significant anti-atherosclerotic activities in preclinical studies by simultaneously counteracting the aforementioned pathogenic mechanisms (Si and Lai, 2024)
