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But, if Reddit is any indication, plenty of women do report period changes on GLP-1s, including: Changes in bleeding or PMS symptoms Cycle regularity A stop to their periods Heres a sampling of the Reddit comments youll find on the topic: I have PCOS and haven't had a period in something like 5 years

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Gallbladder disease Tirzepatide and other GLP-1 drugs delay gallbladder emptying