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Allopurinol, the first-line ULT, suffers from reduced efficacy in patients with impaired conversion to its active metabolite, oxypurinol (OXY), and carries risks of severe hypersensitivity reactions (Mohamad et al., 2025
PubMed / International Journal of Molecular Sciences
We did see that in many cases, the businesses are referring to the compounded medication, or they're using the term FDA approved across their website, DiStefano said
Its our greatest defender against oxidative stress, aiding in detoxification and repairing damaged cells