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Phase 3: Continued escalation (weeks 9 through 12) Dose: 1.0 mg once weekly At 1 mg, the appetite effects become pronounced for most people
For example, you might exercise less, which can make it harder to drift off, or eat less, which can cause nighttime hunger pangs
Originally, GLP-1 likely evolved to control metabolism or processes linked to feeding status, says Karolina Skibicka PhD, professor of nutritional neuroscience at the Hotchkiss Brain Institute, University of Calgary
Another theory is that semaglutide, which belongs to a group of medications called GLP-1 receptor agonists, may cause nausea by activating GLP-1 receptors in the brain, which helps control appetite and blood sugar levels