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These include: Metformin (used for diabetes or PCOS) Proton Pump Inhibitors (used for acid reflux or GERD) H2 Blockers Birth control pills Certain antibiotics If youre taking these medications long-term, particularly in combination, regular B12 injections might be beneficial

Durieux, N., Vandenput, S., & Pasleau, F

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Additional excipients Some compounded formulations include additional ingredients like vitamin B12 , glycine , or other compounds