The delayed onset of the rash, with extension onto areas with less UVR exposure, along with the observed finding of inflammation and ulcerations of mucous membranes, supports that UVR triggered a systemic immune response that is consistent with SJS/TEN, even though sun-exposed areas remained the most severely affected
As proteins rich in disulfides are highly expressed in secretory organs, the cells in these tissues are more susceptible to ER stress
Hyperthyroidism, a condition characterized by excessive production of thyroid hormones, manifests in several distinct types based on their underlying causes
Alpha(1)-adrenoceptor antagonists have also been shown to improve hepatic microvascular dysfunction by significantly reducing hepatic erythrocyte accumulation, thereby effectively alleviating APAP-induced liver injury
Development 127:22692282 Grimaldi G Jr, Soares MJ, Moriearty PL (1984) Tissue eosinophilia and Leishmania mexicana mexicana eosinophil interactions in murine cutaneous leishmaniasis
