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Month 3 and Beyond: This is the phase of systemic support

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Zinc Plays a key role in skin healing, inflammation control, and melanin regulation, helping to minimise post-inflammatory hyperpigmentation

A clear example of this relationship can be observed after the administration of tocilizumab, an IL-6 receptor antagonist that restores the number and cytotoxic activity of CD4 and CD8 T lymphocytes (145)

Regardless of the cause of the deficiency, initial treatment with parenteral B12 was regarded as the first choice for patients with acute and severe manifestations of B12 deficiency