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The conceptual case is genuinely interesting and grounded in real neuroscience, but it hasnt been tested head-to-head against medication in the way GLP-1 drugs themselves have been tested against placebo

Efficacy and safety of pomegranate juice on improvement of erectile dysfunction in male patients with mild to moderate erectile dysfunction: a randomized, placebo-controlled, double-blind, crossover study

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Future research should incorporate more multidimensional individual stratification metrics and conduct prospective cohort studies to identify optimal intervention protocols for different populations, thereby promoting the transition of circadian rhythm interventions from population-based to individualized approaches