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Seven were diagnosed with nonarteritic anterior ischemic optic neuropathy (NAION), one with bilateral papillitis and one with paracentral acute middle maculopathy
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Participants taking 1 mg per week of semaglutide lost about 14 pounds and lowered their A1c by 1.8 percentage points on average, while those taking 1.5 mg per week of dulaglutide lost an average 6.5 pounds and took 1.4 percentage points off their A1c
Future Research Priorities in Safety and Tolerability Despite the promising role of GLP-1-based therapies, several areas require further investigation to ensure their long-term safety in adolescents: Long-Term Metabolic Effects: Future studies should evaluate how sustained GLP-1RA use affects insulin sensitivity, lipid metabolism, and cardiovascular health over decades
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