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Taken together, these data demonstrate the feasibility of Drosophila for the study of acetaminophen toxicity, bringing with it an ease of genetic and microbiome manipulation, high-throughput screening, and availability of transgenic animals

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In this study, when the protein profile of the liver and kidney was investigated with SDS-PAGE, MTX did not change the liver protein profile, but it caused a decrease in some protein bands in the kidney tissue

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M.KleinR.et al (1996)

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It acts as an inhibitor of nicotinamide N-methyltransferase (NNMT), a crucial enzyme involved in energy metabolism and fat storage

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