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(2) Microglia phagocytose myelin debris, which is important as myelin debris can inhibit OPC differentiation, while efficient clearance of myelin debris allows for effective remyelination after experimental demyelination in rodents (Kotter, 2006

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Reported EC50 values include: GIP receptor: Approximately 0.064 nM GLP-1 receptor: Approximately 0.775 nM Glucagon receptor: Approximately 5.79 nM In research models, retatrutide activates several metabolic pathways

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