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We hypothesized that the membrane depolarization could be caused by a coupled transport of l-valine with positively charged Na + -ions into the GLP-1 secreting L-cells

When high serum levels of resistin and leptin were combined, the reduction in food intake induced by leptin decreased in magnitude

We further determined the structures of the D168G SfThi4 mutant that was selected during our directed evolution campaign at 1.4 (X-ray) and 2.84 (cryo-EM) resolution

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As a result of data availability and limited sample size, two cohorts were analyzed in this study: the HbA1c cohort and the BMI cohort