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CTAs were semi-automatically analyzed with an in-house tool for rapid vascular analysis: anatomical markers of the intracerebral segment spanning from the internal carotid artery (ICA) bifurcation to the occlusion, and the cervical ICA tortuosity index (ICA-TI), were extracted

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ALS monocyte-derived microglia-like cells reveal cytoplasmic TDP-43 accumulation, DNA damage, and cell-specific impairment of phagocytosis associated with disease progression

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