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It also partially activates the expression of GSH, GPX4, and SLC7A11, and inhibits the expression of ROS and IL-18 [156]

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PMC6739475 Wiley / Food Frontiers Updated review on NMN and NR mechanisms: NAD+-SIRT1-PGC-1 axis, PARP-1 hyperactivation, and neurodegeneration (peer-reviewed, 2024/2025) PMC / NIH Nicotinamide mononucleotide research in cardiovascular biology