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11.2 What GLP-1 Therapy Does Change GLP-1 receptor agonists consistently: Reduce caloric intake Narrow food volume Alter dietary patterns Increase early satiety Promote rapid weight loss in responders These behavioural and physiological changes shift nutritional exposure

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With a half-life of ~30 minutes it produces pulsatile GH release mimicking natural GH secretion rhythms making it the preferred GHRH analog for physiologically accurate GH pulse research

doi: 10.3103/S0095452719060112 24