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Thyroid hormones increase basal metabolism and thus oxidative metabolism by inducing specific mitochondrial enzymes [29]

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Measurement of plasma HbA1c concentration HbA1c concentration in plasma samples collected from DIO mice at 8, 16, and 24 weeks after the initial treatment of the pharmacodynamic study was determined using a mouse HbA1c ELISA kit (Aviva Systems Biology) according to the manufacturers protocols