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Because liver failure patients are prone to a variety of other medical problems that can lead to encephalopathy (such as coagulopathy associated intracranial hemorrhage, electrolyte disarray, renal failure, hypotension, hypoglycemia, and infection), a thorough history, physical and neurologic examination is mandated in all encephalopathic liver failure patients

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Total bilirubin is the sum of two forms of bilirubin in the blood: direct (conjugated) bilirubin and indirect (unconjugated) bilirubin