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Acute gallbladder disease: Pain in the middle or right upper stomach, fever, white parts of your eyes or skin turning yellow or skin turns yellow, nausea/vomiting

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in the other outcome, the injured tissue continues to deteriorate, and the mechanism of the persisting damage involves gliosis with the loss of support of neurotrophic factors, persistent inflammatory receptor activation, and changes in microglia and astrocytes that continue to release harmful cytokines, which promote neuronal death and axonal injury

It affects everything from mental health to cardiovascular disease risk to hormone balance, and plays a role in how your body synthesizes melatonin for sleep, glutathione for antioxidant defence, and creatine for muscle performance