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Detection was performed using the Thermo Scientific Dionex UltiMate 3000 HPLC system equipped with a binary pump and bypassed column, in conjunction with a triple quadrupole mass spectrometer in positive electrospray ionization mode

Any consideration of investigational approaches should occur only within the context of clinical trials or with explicit acknowledgment of the limited evidence base and careful risk-benefit assessment tailored to your specific clinical circumstances

Assessments during treatment included standard laboratory testing, serum HCV RNA, vital signs, electrocardiography, and symptom-directed physical examinations

Alternative methods add complexity without meaningful benefit for typical peptide use

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