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TB-500 binds monomeric G-actin through the central LKKTETQ motif, sequestering actin monomers and modulating the cytoplasmic pool available for filament elongation in cell-based assays

Consumption of these products has resulted in numerous hospitalizations, [2] and the drugs have been reported to cause hallucinations, increased heartbeat and blood pressure, aggressive behavior, anxiety, muscle spasms, nausea, and vomiting