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This modulation of inflammatory signaling occurs through activation of the PI3K/AKT pathway, which possesses intrinsic anti-inflammatory properties including inhibition of pro-inflammatory cytokine release and enhancement of cellular stress resistance

10.1016/j.mam.2022.101112 [DOI] [PubMed] [Google Scholar] Associated Data This section collects any data citations, data availability statements, or supplementary materials included in this article

In early stages of prediabetes or mild type 2 diabetes, significant lifestyle changes-such as losing 5-10% of body weight, adopting a low-carb or Mediterranean diet, and exercising regularly-can sometimes lower A1C enough to delay or avoid medication

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