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This can now undergo one cycle of oxidation to yield 4 Z -10:1-CoA, which is acted upon by an acyl-CoA dehydrogenase to produce 2 E ,4 Z -10:2-CoA before this in turn is the substrate for an NADPH-dependent 2,4dienoyl-CoA reductase to generate 3 E -10:1-CoA

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Glutamic acid can also be synthesized endogenously in the human body through the transamination of alpha-ketoglutarate, a key intermediate of the TCA cycle

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