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Cui S, Simmons G Jr, Vale G, Deng Y, Kim J, Kim H, et al

Glutathione peroxidase converts the reduced glutathione (GSH) to its oxidized form (GSSG) in the following reaction: In animals, this enzyme was studied extensively and found in two forms namely selenium (Se) dependent GPX and selenium independent GPX (Wendel, 1980

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The data on insulin secretion, insulin sensitivity, and glucose homeostasis were confirmed in the phase II clinical study (clinical trials registration number NCT03131687) (62)