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The studies showed that survodutide therapy led to a maximum placebo-corrected body weight loss of 13.8% by week 16, demonstrating its potential for significant weight loss [110]

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Incretin-based drugs are now being investigated and in some cases approved for a wide range of conditions, including cardiovascular disease, chronic kidney disease, sleep apnea, fatty liver disease (MASLD), neurodegenerative disorders, and even substance-use disorders

About 1 in 8 Americans uses GLP-1 drugs for diabetes, weight loss and other chronic conditions, including semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro, Zepbound)

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