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Amylin has several characteristics of a satiating hormone: 1) it is released after food ingestion ( via central mechanisms ( Taken together, amylin has acute effects as a satiety signal combined with homeostatic effects of an adiposity signal on body weight, suggesting an important role of amylin in the regulation of body mass

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N Engl J Med 380(24):22952306 Kristensen SL, Rrth R, Jhund PS, Docherty KF, Sattar N, Preiss D et al (2019) Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials

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Comparing Oral GLP-1s with Injections The Next Wave of Oral GLP-1s Eli Lillys orforglipron could be a game-changer in oral GLP-1 medications